反应详情

A solution of 2-[(5-ethoxycarbonylmethoxy-1,2,3,4-tetrahydro-1-naphthyl)methoxycarbonyl]-1,1-diphenylhydrazine (0.17 g) and 1N-aqueous sodium hydroxide (1 ml) in dioxane (1.5 ml) was stirred at room temperature for 30 minutes and partitioned between 5% hydrochloric acid and ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, and evaporated in vacuo. The residue was washed with isopropanol to afford 2-[(5-carboxymethoxy-1,2,3,4-tetrahydro-1-naphthyl)-methoxycarbonyl]-1,1-diphenylhydrazine (0.08 g) as a colorless powder.

1. custompartitioned between 5% hydrochloric acid and ethyl acetate
2. washThe organic layer was washed with brine
3. dry with materialdried over sodium sulfate
4. customevaporated in vacuo
5. washThe residue was washed with isopropanol