Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Chloride → Methyl(4-benzylthiophenyl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Chloride | HCID 7503 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Methyl 2-(4-mercaptophenyl)acetate | HCID 14033178 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Methyl(4-benzylthiophenyl)acetate | HCID 54174016 | — |
반응 단계
Methyl(4-mercaptophenyl)acetate (0.2 mol) is heated at reflux with benzyl chloride (25 g, 0.2 mol) and K2CO3 (25 g, 0.2 mol) in 100 mL ethanol. The product is added to aqueous NaOH, extracted with ether, and purified by silica gel chromatography to yield methyl(4-benzylthiophenyl)acetate (3). (Scheme III, Step 1.)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04761420 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-3bd374c3ce354367ba30e6cb8a4808a1 |
| 출처 메모 | uspto-grants-1988_08 |