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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344108Generated: October 26, 2026

Trifluoroacetic acid → 2-[4-(2-Butylbenzimidazol-1-yl)methylphenyl]benzoic acid

https://huagongshe.com/reaction/344108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert.butyl 4'-[(2-n-butyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylateHCID 67572640—
SolventDichloromethaneHCID 6344—
Product2-[4-(2-Butylbenzimidazol-1-yl)methylphenyl]benzoic acidHCID 4110026—

Reaction Steps

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864043
Source datasetuspto-grants-1999_01
ORD IDord-037746ec43084fd48449ec362dadb9d1
Source noteuspto-grants-1999_01