Sodium Hydroxide → HCID 86749679, compound

HRID 344122Notes

Reaction equation

[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25]CC)=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:28]=[CH:29][C:30]([N:32]([NH:36][C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[C:33]([CH3:35])=[O:34])=[CH:31][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].[OH-].[Na+]>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[C:18]([C:23]([OH:25])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:15][CH:16]=2)[C:8]2[CH:28]=[CH:29][C:30]([N:32]([NH:36][C:37]([O:39][C:40]([CH3:41])([CH3:43])[CH3:42])=[O:38])[C:33]([CH3:35])=[O:34])=[CH:31][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 86749680HCID 86749680, compound

Product 1

HCID 86749679HCID 86749679, compound

Procedure

Prepared in analogous manner to Example 72 from ethyl 4'-[(2-n-butyl-5-(tert.butoxycarbonylaminoacetamino)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and 2N sodium hydroxide.

Sources & evidence

ORD record: ord-def0acbfd3104a719a6d2ef4a40faa49
Source dataset: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05864043

Reaction notes

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