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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344132Generated: October 26, 2026

Trifluoroacetic acid → 4'-[(2-(3-Methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid

https://huagongshe.com/reaction/344132

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert.butyl 4'-[(2-(3-methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylateHCID 15069182—
SolventDichloromethaneHCID 6344—
Product4'-[(2-(3-Methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acidHCID 15069360—

Reaction Steps

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-(3-methylbutyl)-5,6-dimethoxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864043
Source datasetuspto-grants-1999_01
ORD IDord-32fedbddc3704edc882f4ca0f7cc5f0e
Source noteuspto-grants-1999_01