Sodium hydroxide ethanol → HCID 67572386, compound

HRID 344191Notes

Reaction equation

HRID 344191 reaction equation
[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25]CC)=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:28]=[C:29]([N:32]([CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][OH:41])[C:33]([NH2:35])=[O:34])[CH:30]=[CH:31][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].[OH-].[Na+].C(O)C>>[OH2:24].[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[C:18]([C:23]([OH:25])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:15][CH:16]=2)[C:8]2[CH:28]=[C:29]([N:32]([CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][OH:41])[C:33]([NH2:35])=[O:34])[CH:30]=[CH:31][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 23692425Sodium hydroxide ethanolHCID 57303418HCID 57303418, compound

Product 1

HCID 67572386HCID 67572386, compound

Procedure

Prepared in analogous manner to Example 72 from ethyl 4'-[(2-n-butyl-6-((5-hydroxy-n-pentyl)-aminocarbonyl-amino)-benzimidazol-1-yl)methyl]biphenyl-2-carboxylate and 2N NaOH/ethanol.

Sources & evidence

ORD record
ord-a49a00c34c3943e696c6bc6db95add27
Source dataset
uspto-grants-1999_01
Patent number
US05864043

Reaction notes

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