HCID 57252249, compound → HCID 57007033, compound

HRID 344219Notes

Reaction equation

HRID 344219 reaction equation
[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25]CC)=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:28]=[C:29]([N:32]([CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])[C:33]([NH:35][CH:36]3[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]3)=[O:34])[CH:30]=[CH:31][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]>C(O)C>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[C:18]([C:23]([OH:25])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:15][CH:16]=2)[C:8]2[CH:28]=[C:29]([N:32]([CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49])[C:33]([NH:35][CH:36]3[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]3)=[O:34])[CH:30]=[CH:31][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 57252249HCID 57252249, compound

Product 1

HCID 57007033HCID 57007033, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared in analogous manner to Example 72 from ethyl 4'-[(2-n-butyl-6-(N-(cyclohexylamino-carbonyl)-n-octylamino)-benzimidazol-1-yl)-methyl)bi-phenyl-2-carboxylate in ethanol/2N sodium hydroxide solution.

Sources & evidence

ORD record
ord-c150ef6e3aa94ab392fce52493d4cee5
Source dataset
uspto-grants-1999_01
Patent number
US05864043

Reaction notes

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