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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344222Generated: October 31, 2026

Trifluoroacetic acid → 4'-[(2-n-butyl-6-(2-phenylethylaminocarbonyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic Acid

https://huagongshe.com/reaction/344222

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert.-butyl 4'-[(2-n-butyl-6-(2phenylethylamino-carbonyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylateHCID 67572612—
SolventDichloromethaneHCID 6344—
Product4'-[(2-n-butyl-6-(2-phenylethylaminocarbonyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic AcidHCID 54454545—

Reaction Steps

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-6-(2-phenylethylamino-carbonyl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864043
Source datasetuspto-grants-1999_01
ORD IDord-b4772916158c4dc19946740b2398a1ec
Source noteuspto-grants-1999_01