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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344226Generated: October 26, 2026

Hydrochloric Acid → 4'-[(2-n-Butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1H-tetrazol-5-yl)-biphenyl

https://huagongshe.com/reaction/344226

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4'-[(2-n-butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)-biphenylHCID 56999388—
SolventDCM ether MeOHHCID 22565053—
Product4'-[(2-n-Butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1H-tetrazol-5-yl)-biphenylHCID 178441527—

Reaction Steps

Prepared in analogous manner to Example 58b from 4'-[(2-n-butyl-5-(N-cyclohexylaminocarbonyl-methylamino)-benzimidazol-1-yl)-methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)-biphenyl and hydrochloric acid in methylene chloride/ether/methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864043
Source datasetuspto-grants-1999_01
ORD IDord-cc6c238da3e24d5796c23f8471612a2e
Source noteuspto-grants-1999_01