Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzyl mercaptan | HCID 7509 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Bromo-5-chloropentane | HCID 96070 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Benzylthiopentyl chloride | HCID 14221119 | 54.3% |
Reaction Steps
Potassium carbonate (5 g) and 1-bromo-5-chloropentane (4.9 g) were added to a solution of benzylmercaptan (3 g) in dimethylformamide (40 ml), and the mixture was stirred at 70-80° C. for 2 hr. Water was added to the reaction mixture and the mixture was extracted with ethyl acetate. The organic layer was washed with brine, dried and the solvent was evaporated under reduced pressure to give 3 g of 5-benzylthiopentyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05864039 |
|---|
| Source dataset | uspto-grants-1999_01 |
|---|
| ORD ID | ord-eeef5c333f2f4c32ace74ee296174bc8 |
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| Source note | uspto-grants-1999_01 |
|---|
