Phenol → HCID 11140208, compound

HRID 344262Notes

Reaction equation

HRID 344262 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14](Cl)=[O:15].[Cl-].[Al+3].[Cl-].[Cl-]>>[Br:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]([C:4]1[CH:5]=[CH:6][C:1]([OH:7])=[CH:2][CH:3]=1)=[O:15]

Participants

4

Reactant 3

HCID 996PhenolHCID 898486-Bromohexanoyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 11140208HCID 11140208, compoundYield 20.1%

Procedure

Phenol (0.88 g), 6-bromohexanoyl chloride (2.0 g) and aluminum chloride (1.4 g) were reacted and treated in the same manner as in Preparation Example 105 to give 0.51 g of 6-bromo-1-(4-hydroxyphenyl)-1-hexanone.

Workup

  1. additiontreated in the same manner as in Preparation Example 105

Sources & evidence

ORD record
ord-8f57e021c3ee45119bbad79fa6d752ac
Source dataset
uspto-grants-1999_01
Patent number
US05864039

Reaction notes

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