Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344271Generated: October 26, 2026

1,3-Difluorobenzene → 6-Bromo-1-(2,4-difluorophenyl)-1-hexanone

https://huagongshe.com/reaction/344271

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DifluorobenzeneHCID 9741—
Reactant6-Bromohexanoyl chlorideHCID 89848—
ReactantAluminum(III) ChlorideHCID 6451240—
Product6-Bromo-1-(2,4-difluorophenyl)-1-hexanoneHCID 54475809—

Reaction Steps

6-Bromohexanoyl chloride (2 g), 1,3-difluorobenzene (20 ml) and aluminum chloride (1.31 g) were reacted and treated in the same manner as in Preparation Example 105 to give 1.16 g of 6-bromo-1-(2,4-difluorophenyl)-1-hexanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-a6e4bc8f0a7d47789098a91f4df4b36b
Source noteuspto-grants-1999_01