HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-Methoxy-1-(6-oxo-6-phenylhexyl)-4-tert-butoxycarbonylaminomethylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Hexanone, 6-bromo-1-phenyl- | HCID 11242260 | — |
| Reactant | tert-butyl N-[(4-methoxypiperidin-4-yl)methyl]carbamate | HCID 54295846 | — |
| Product | 4-Methoxy-1-(6-oxo-6-phenylhexyl)-4-tert-butoxycarbonylaminomethylpiperidine | HCID 54549960 | 85% |
Reaction Steps
4-Methoxy-4-tert-butoxycarbonylaminomethylpiperidine (2.3 g), 6-bromo-1-phenyl-1-hexanone (2.52 g) and potassium carbonate (2.6 g) were reacted and treated in the same manner as in Preparation Example 138(1) to give 3.35 g of 4-methoxy-1-(6-oxo-6-phenylhexyl)-4-tert-butoxycarbonylaminomethylpiperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05864039 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-9a76fb4e7079414791a40632d76a68c6 |
| Source note | uspto-grants-1999_01 |