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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344303Generated: October 31, 2026

4-Amino-5-chloro-2-methoxybenzoic acid → HCID 54203253, compound

https://huagongshe.com/reaction/344303

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
Reactant1-Adamantanecarbonyl chlorideHCID 98915—
ReactantHCID 53780050HCID 53780050—
ProductHCID 54203253HCID 54203253—

Reaction Steps

4-((3R)-3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)butylamine (1.20 g) as starting compound was reacted and treated in the same manner as in Example 1 using 1-adamantanecarbonyl chloride (0.98 g) and 4-amino-5-chloro-2-methoxybenzoic acid (0.85 g) to give N-((3R)-1-(4-(1-adamantanecarbonylamino)butyl)pyrrolidin-3-ylmethyl)-4-amino-5-chloro-2-methoxybenzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-121820fdedfb446c9909c136b8767deb
Source noteuspto-grants-1999_01