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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344304Generated: October 30, 2026

Benzoyl chloride → HCID 22438730, compound

https://huagongshe.com/reaction/344304

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chlorideHCID 7412—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
Reactanttert-Butyl ((1-(2-aminoethyl)pyrrolidin-3-yl)methyl)carbamateHCID 53652257—
ProductHCID 22438730HCID 22438730—

Reaction Steps

2-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)ethylamine (1 g) as starting compound was reacted and treated in the same manner as in Example 1 using benzoyl chloride (0.47 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.83 g) to give 4 -amino-N-(1-(2-benzoylaminoethyl)pyrrolidin-3-ylmethyl)-5-chloro-2-methoxybenzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-2f3cf94bf53646e7a98f1ebe9a9d389e
Source noteuspto-grants-1999_01