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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344319Generated: October 31, 2026

Methyl Isocyanate → HCID 54053224, compound

https://huagongshe.com/reaction/344319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl IsocyanateHCID 12228—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
ReactantHCID 53696622HCID 53696622—
ProductHCID 54053224HCID 54053224—

Reaction Steps

3-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)propylamine (1.12 g) as starting compound was reacted and treated in the same manner as in Example 34 using methyl isocyanate (0.38 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.96 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(3-(3-methylureido)propyl)pyrrolidin-3-ylmethyl)-benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-25d23963603b4cd5a0707671c671cbaa
Source noteuspto-grants-1999_01