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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344328Generated: October 31, 2026

Propyl isocyanate → HCID 57206304, compound

https://huagongshe.com/reaction/344328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropyl isocyanateHCID 61033—
Reactant4-Amino-5-chloro-2-methoxybenzoic acidHCID 81626—
ReactantHCID 53780051HCID 53780051—
ProductHCID 57206304HCID 57206304—

Reaction Steps

4-((3S)-3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)butylamine (1.50 g) as starting compound was reacted and treated in the same manner as in Example 34 using n-propyl isocyanate (0.57 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (1.11 g) to give 4-amino-5-chloro-2-methoxy-N-((3S)-1-(4-(3-n-propylureido)butyl)pyrrolidin-3-ylmethyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-e03b213faed641ce83d534589862307b
Source noteuspto-grants-1999_01