HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl isocyanate → 4-amino-5-chloro-2-methoxy-N-(1-(4-(3-phenylureido)butyl)pyrrolidin-3-ylmethyl)-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | 4-Amino-5-chloro-2-methoxybenzoic acid | HCID 81626 | — |
| Reactant | HCID 53780052 | HCID 53780052 | — |
| Product | 4-amino-5-chloro-2-methoxy-N-(1-(4-(3-phenylureido)butyl)pyrrolidin-3-ylmethyl)-benzamide | HCID 53703828 | — |
Reaction Steps
4-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)butylamine (0.92 g) as starting compound was reacted and treated in the same manner as in Example 34 using phenyl isocyanate (0.37 ml) and 4-amino-5-chloro-2-methoxybenzoic acid (0.68 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(4-(3-phenylureido)butyl)pyrrolidin-3-ylmethyl)-benzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05864039 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-8b506cd1bce14d1d93bd6ccf9e0c4a1d |
| Source note | uspto-grants-1999_01 |