4-Chlorophenyl Isocyanate → HCID 54056267, compound

Participants

Reaction Steps

5-(4-tert-Butoxycarbonylaminomethylpiperidin-1-yl)pentylamine (2.00 g) was dissolved in methylene chloride (80 ml) and a solution of 4-chlorophenyl isocyanate (1.13 g) in methylene chloride was dropwise added under ice-cooling. The mixture was stirred at room temperature for 15 hr, and the reaction mixture was concentrated under reduced pressure to give 4-tert-butoxycarbonylaminomethyl-1-(5-(3-(4-chlorophenyl)ureido)pentyl)piperidine.

Provenance & Evidence