4-Amino-5-chloro-2-methoxybenzoic acid → HCID 54037148, compound

HRID 344356Notes

Reaction equation

HRID 344356 reaction equation
C(O[C:6]([NH:8][CH2:9][CH:10]1[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][NH:18][C:19]([C:21]2[CH:26]=[CH:25][N:24]=[CH:23][CH:22]=2)=[O:20])[CH2:11]1)=[O:7])(C)(C)C.[NH2:27][C:28]1[C:36]([Cl:37])=[CH:35][C:31](C(O)=O)=[C:30]([O:38][CH3:39])[CH:29]=1>>[NH2:27][C:28]1[C:36]([Cl:37])=[CH:35][C:31]([C:6]([NH:8][CH2:9][CH:10]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][NH:18][C:19]([C:21]3[CH:22]=[CH:23][N:24]=[CH:25][CH:26]=3)=[O:20])[CH2:11]2)=[O:7])=[C:30]([O:38][CH3:39])[CH:29]=1

Participants

3

Reactant 2

HCID 816264-Amino-5-chloro-2-methoxybenzoic acidHCID 53933370HCID 53933370, compound

Product 1

HCID 54037148HCID 54037148, compound

Procedure

N-(3-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)propyl)-4-pyridinecarboxamide (0.90 g) as starting compound was reacted and treated in the same manner as in Example 67 using 4-amino-5-chloro-2-methoxybenzoic acid (0.50 g) to give 4-amino-5-chloro-2-methoxy-N-(1-(3-(4-pyridinecarbonylamino)propyl)pyrrolidin-3-ylmethyl)benzamide.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-057c22939639421abec67edea844734b
Source dataset
uspto-grants-1999_01
Patent number
US05864039

Reaction notes

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