HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-5-chloro-2-methoxybenzoic acid → 4-amino-N-(1-(4-(N-benzoyl-N-methylamino)butyl)pyrrolidin-3-ylmethyl)-5-chloro-2-methoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-5-chloro-2-methoxybenzoic acid | HCID 81626 | — |
| Reactant | N-(4-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)butyl)-N-methylbenzamide | HCID 53789127 | — |
| Product | 4-amino-N-(1-(4-(N-benzoyl-N-methylamino)butyl)pyrrolidin-3-ylmethyl)-5-chloro-2-methoxybenzamide | HCID 53841373 | — |
Reaction Steps
N-(4-(3-tert-Butoxycarbonylaminomethylpyrrolidin-1-yl)butyl)-N-methylbenzamide (0.57 g) as starting compound was reacted and treated in the same manner as in Example 67 using 4-amino-5-chloro-2-methoxybenzoic acid (0.30 g) to give 4-amino-N-(1-(4-(N-benzoyl-N-methylamino)butyl)pyrrolidin-3-ylmethyl)-5-chloro-2-methoxybenzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05864039 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-fa013027c84541a1962ea6c276888067 |
| Source note | uspto-grants-1999_01 |