4-Amino-5-chloro-2-methoxybenzoic acid → Benzamide

HRID 344376Notes

Reaction equation

HRID 344376 reaction equation
C(OC([NH:8]CC1CCN(CCNS(C)(=O)=O)C1)=O)(C)(C)C.N[C:23]1[C:31](Cl)=[CH:30][C:26]([C:27](O)=[O:28])=[C:25](OC)[CH:24]=1>>[C:27]([NH2:8])(=[O:28])[C:26]1[CH:30]=[CH:31][CH:23]=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 816264-Amino-5-chloro-2-methoxybenzoic acidHCID 54265263HCID 54265263, compound

Product 1

HCID 2331Benzamide

Procedure

3-tert-Butoxycarbonylaminomethyl-1-(2-methylsulfonylaminoethyl)pyrrolidine (2 g) as starting compound was reacted and treated in the same manner as in Example 67 using 4-amino-5-chloro-2-methoxybenzoic acid (1.25 g) to give 4-amino-5-chloro-2-methoxy-N-(2-methylsulfonylaminoethyl)pyrrolidin-3-ylmethyl)benzamide.

Workup

  1. customwas reacted

Sources & evidence

ORD record
ord-4f6b72c627c9469593a588126a673646
Source dataset
uspto-grants-1999_01
Patent number
US05864039

Reaction notes

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