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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344406Generated: October 30, 2026

4-Methoxybenzaldehyde → 4-amino-5-chloro-N-((1-(6-(4-methoxybenzylamino)hexyl)piperidin-4-yl)methyl)-2-methoxybenzamide

https://huagongshe.com/reaction/344406

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzaldehydeHCID 31244—
Reactant4-Amino-N-(1-(6-aminohexyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamideHCID 53683637—
Product4-amino-5-chloro-N-((1-(6-(4-methoxybenzylamino)hexyl)piperidin-4-yl)methyl)-2-methoxybenzamideHCID 5391374757.8%

Reaction Steps

4-Amino-N-(1-(6-aminohexyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide (1.5 g) as starting compound and 4-methoxylbenzaldehyde (0.56 g) were reacted and treated in the same manner as in Example 121 to give 1.13 g of 4-amino-5-chloro-N-((1-(6-(4-methoxybenzylamino)hexyl)piperidin-4-yl)methyl)-2-methoxybenzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-dd9fccaa5047407db32eb14123dd66be
Source noteuspto-grants-1999_01