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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344463Generated: October 30, 2026

Potassium Carbonate → HCID 54125270, compound

https://huagongshe.com/reaction/344463

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 54318304HCID 54318304—
Reactant4-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochlorideHCID 69966330—
ProductHCID 54125270HCID 5412527064.2%

Reaction Steps

4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride (1.0 g) as starting compound, potassium carbonate (1.5 g) and 6-bromo-1-(3-fluoro-4-methoxyphenyl)-1-hexanone (0.94 g) were reacted and treated in the same manner as in Example 172 to give 0.90 g of 4-amino-5-chloro-N-((1-(6-(3-fluoro-4-methoxyphenyl)-6-oxohexyl)-piperidin-4-yl)methyl)-2-methoxybenzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-f4eaf27b5aa1438eadbd40bb467eaa9e
Source noteuspto-grants-1999_01