HCID 43168553, compound → HCID 54173671, compound

HRID 344505Notes

Reaction equation

HRID 344505 reaction equation
Cl.Cl.[NH2:3][C:4]1[C:19]([Cl:20])=[CH:18][C:7]([C:8]([NH:10][CH2:11][CH:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)=[O:9])=[C:6]([O:21][CH3:22])[CH:5]=1.[C:23]1([CH2:29][CH2:30][O:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]Cl)[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[NH2:3][C:4]1[C:19]([Cl:20])=[CH:18][C:7]([C:8]([NH:10][CH2:11][CH:12]2[CH2:13][CH2:14][N:15]([CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][O:31][CH2:30][CH2:29][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH2:16][CH2:17]2)=[O:9])=[C:6]([O:21][CH3:22])[CH:5]=1

Participants

3

Reactant 2

HCID 43168553HCID 43168553, compoundHCID 699663304-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride

Product 1

HCID 54173671HCID 54173671, compound

Procedure

4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride (2.0 g) as starting compound and 5-(2-phenylethyloxy)-pentyl chloride were reacted and treated in the same manner as in Example 168 to give 0.69 g of 4-amino-5-chloro-2-methoxy-N-((1-(5-(2-phenylethyloxy)pentyl)piperidin-4-yl)methyl)benzamide.

Workup

  1. customwere reacted
  2. additiontreated in the same manner as in Example 168

Sources & evidence

ORD record
ord-d6693718b1834828935c91dcee218d2a
Source dataset
uspto-grants-1999_01
Patent number
US05864039

Reaction notes

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