HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylmercapto-butylbromide → 4-amino-5-chloro-2-methoxy-N-((1-(4-phenylthiobutyl)piperidin-4-yl)methyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylmercapto-butylbromide | HCID 11184148 | — |
| Reactant | 4-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride | HCID 69966330 | — |
| Product | 4-amino-5-chloro-2-methoxy-N-((1-(4-phenylthiobutyl)piperidin-4-yl)methyl)benzamide | HCID 53804311 | 27% |
Reaction Steps
4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride (2.5 g) as starting compound and 4-phenylthiobutyl bromide (2.48 g) were reacted and treated in the same manner as in Example 168 to give 0.84 g of 4-amino-5-chloro-2-methoxy-N-((1-(4-phenylthiobutyl)piperidin-4-yl)methyl)benzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05864039 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-97e64f68915e4d798483ce964c784faa |
| Source note | uspto-grants-1999_01 |