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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344514Generated: October 31, 2026

5-(3-Methoxybenzyloxy)pentyl bromide → 4-amino-5-chloro-2-methoxy-N-((1-(5-(3-methoxybenzyloxy)pentyl)-piperidin-4-yl)methyl)benzamide

https://huagongshe.com/reaction/344514

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3-Methoxybenzyloxy)pentyl bromideHCID 54316557—
Reactant4-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochlorideHCID 69966330—
Product4-amino-5-chloro-2-methoxy-N-((1-(5-(3-methoxybenzyloxy)pentyl)-piperidin-4-yl)methyl)benzamideHCID 53634339—

Reaction Steps

4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride as starting compound and 5-(3-methoxybenzyloxy)pentyl bromide are reacted and treated in the same manner as in Example 168 to give 4-amino-5-chloro-2-methoxy-N-((1-(5-(3-methoxybenzyloxy)pentyl)-piperidin-4-yl)methyl)benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-890c1f6990b544e594fa66eaa5064d87
Source noteuspto-grants-1999_01