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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344540Generated: October 26, 2026

3-Chloropropyl phenyl sulfide → 4-amino-5-chloro-2-methoxy-N-((1-(3-(phenylthio)propyl)piperidin-4-yl)methyl)-benzamide

https://huagongshe.com/reaction/344540

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloropropyl phenyl sulfideHCID 269606—
Reactant4-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochlorideHCID 69966330—
Product4-amino-5-chloro-2-methoxy-N-((1-(3-(phenylthio)propyl)piperidin-4-yl)methyl)-benzamideHCID 54506693—

Reaction Steps

4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride and 3-phenylthiopropyl chloride were reacted and treated in the same manner as in Example 168 to give 4-amino-5-chloro-2-methoxy-N-((1-(3-(phenylthio)propyl)piperidin-4-yl)methyl)-benzamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05864039
Source datasetuspto-grants-1999_01
ORD IDord-b75dcdf56aad4dd692ec78e6e7a6d1ab
Source noteuspto-grants-1999_01