HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiophenecarboxaldehyde → HCID 53944756, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiophenecarboxaldehyde | HCID 7364 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 4-Amino-N-(1-(6-aminohexyl)piperidin-4-ylmethyl)-5-chloro-2-methoxybenzamide | HCID 53683637 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 53944756 | HCID 53944756 | 40.3% |
Reaction Steps
4-Amino-5-chloro-2-methoxy-N-((1-(6-aminohexyl)piperidin-4-yl)-methyl)benzamide (2.0 g), 2-thiophenecarboxaldehyde (0.62 g), sodium borohydride (0.42 g) and ethanol (40 ml) were reacted and treated in the same manner as in Example 121 to give 1.0 g of 4-amino-5-chloro-2-methoxy-N-((1-(6-(2-thienylmethylamino)hexyl)piperidin-4-yl)-methyl)benzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05864039 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-20435ea43ba24217bd49025bb1581a72 |
| Source note | uspto-grants-1999_01 |