HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54183214, compound → HCID 54317143, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54183214 | HCID 54183214 | — |
| Reactant | 4-amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride | HCID 69966330 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 54317143 | HCID 54317143 | 18.4% |
Reaction Steps
4-Amino-5-chloro-2-methoxy-N-(piperidin-4-ylmethyl)benzamide dihydrochloride (3.87 g) as a starting compound, 6-bromo-1-(2,4-dihydroxyphenyl)-1-hexanone (3.00 g) and triethylamine (6.5 ml) were reacted and purified in the same manner as in Example 172 to give 0.97 g of 4-amino-5-chloro-2-methoxy-N-((1-(6-(2,4-dihydroxyphenyl)-6-oxohexyl)piperidin-4-yl)methyl)benzamide, m.p. 96°-99° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05864039 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-8319b512c5b74333be0cf4929588145d |
| Source note | uspto-grants-1999_01 |