2-Mercaptoethanol → HCID 14362083, compound

HRID 344564Notes

Reaction equation

HRID 344564 reaction equation
[SH:1][CH2:2][CH2:3][OH:4].[C:5]1(=[O:12])[CH:10]=[CH:9][C:8](=[O:11])[CH:7]=[CH:6]1>C(O)C>[OH:4][CH2:3][CH2:2][S:1][C:10]1[C:5](=[O:12])[CH:6]=[CH:7][C:8](=[O:11])[CH:9]=1

Participants

4

Reactant 2

HCID 15672-MercaptoethanolHCID 4650Quinone

Product 1

HCID 14362083HCID 14362083, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Mercaptoethanol (25.9 ml, 0.368 mole) is added in a single amount to a suspension of p-benzoquinone (80 g, 0.736 mole) in absolute ethanol (500 ml), with stirring and while bubbling nitrogen through the suspension. The temperature rises from 22° C. to 45° C. within 30 seconds and the mixture becomes a homogeneous red-brown. At the end of 15 minutes, a precipitate appears. The mixture is left to stand with stirring for 2 hours and filtered through a no. 4 frit. The orange-red precipitate is washed with 3×50 ml of cold ethanol and dried. Orange crystals are obtained

Workup

  1. customwhile bubbling nitrogen through the suspension
  2. customAt the end of 15 minutes
  3. waitThe mixture is left
  4. stirringwith stirring for 2 hours
  5. filtrationfiltered through a no
  6. washThe orange-red precipitate is washed with 3×50 ml of cold ethanol
  7. customdried
  8. customOrange crystals are obtained

Sources & evidence

ORD record
ord-4e83e0bed5d84f3ba052c89ce64545d6
Source dataset
uspto-grants-1991_10
Patent number
US05053053

Reaction notes

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