反应详情

A mixture of 8.0 g of 32D and 80 mL of Dowtherm® was heated at 200°-250° C. for 2 hours, cooled to room temperature, diluted with petroleum ether and filtered. The collected solid phase was dried under reduced pressure, and recrystallized from ethyl acetate/petroleum ether to give 2-(7-chloro-2,3-dihydro-2-methyl-4-benzofuranyl)-1,2,4-triazine-3,5(2H,4H)-dione, (32E) as a tan solid, m.p.: 184°-186° C.

1. temperaturewas heated at 200°-250° C. for 2 hours
2. filtrationfiltered
3. customThe collected solid phase was dried under reduced pressure
4. customrecrystallized from ethyl acetate/petroleum ether