HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 344669Generated: October 30, 2026
4-Aminopyridine → Acetic acid--N-(pyridin-4-yl)acetamide (1/1)
https://huagongshe.com/reaction/344669
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Product | Acetic acid--N-(pyridin-4-yl)acetamide (1/1) | HCID 67923113 | 88.3% |
Reaction Steps
4-Aminopyridine (101.28 g) and acetic anhydride (110 g) were mixed neat and heated at 100° C. for 1/2 h. The solidified reaction mixture was triturated with acetone, filtered off, and washed with ether to afford 186.48 g of title compound as a white solid in two crops.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05053413 |
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| Source dataset | uspto-grants-1991_10 |
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| ORD ID | ord-70630576f7fa4fdf9a289b0a26d56d9a |
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| Source note | uspto-grants-1991_10 |
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