1-Benzyl-4-piperidylamine → HCID 15020384, compound

HRID 344671Notes

Reaction equation

HRID 344671 reaction equation
[C:1]1([CH2:7][N:8]2[CH2:13][CH2:12][CH:11]([NH2:14])[CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C([O:18][CH2:19][CH3:20])(=O)C.[CH3:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>>[C:1]1([CH2:7][N:8]2[CH2:13][CH2:12][CH:11]([N:14]3[CH2:26][C:25]4[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=4)[C:19]3=[O:18])[CH2:10][CH2:9]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 4158521-Benzyl-4-piperidylamineHCID 21226206Ethyl acetate hexane

Product 1

HCID 15020384HCID 15020384, compound

Procedure

Following the procedure outlined in Example 6 and substituting commercially available 1 phenylmethyl 4-aminopiperidine (2.29 g), 0.60 g of product was isolated as a white crystalline solid from ethyl acetate/skellysolve B: mp 116-118° C. Anal. calcd for C20H22N2O 0.25 H20: C, 77.26; H, 7.29; N, 9.01. Found: C, 77.65; H, 7.38; N, 9.08.

Sources & evidence

ORD record
ord-8fe64e0da89e41ca95798761d1263552
Source dataset
uspto-grants-1991_10
Patent number
US05053413

Reaction notes

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