1,2-Dibromoethane → 1H-1,2,4-Triazole

HRID 344674Notes

Reaction equation

HRID 344674 reaction equation
[NH:1]1[CH:5]=[N:4][CH:3]=[N:2]1.C(OC([C:11]1C=C(C(OCC)=O)[NH:13][N:12]=1)=O)C.BrC[CH2:23][Cl:24].BrCCBr>>[N:4]1([CH2:3][CH2:23][Cl:24])[CH:5]=[CH:11][N:12]=[N:13]1.[NH:1]1[CH:5]=[N:4][CH:3]=[N:2]1

Participants

6

Reactant 4

HCID 78391,2-DibromoethaneHCID 78491-Bromo-2-ChloroethaneHCID 92571H-1,2,4-TriazoleHCID 142184diethyl 1H-pyrazole-3,5-dicarboxylate

Product 2

HCID 92571H-1,2,4-TriazoleHCID 12506800HCID 12506800, compound

Procedure

When an equivalent amount of 1,2,4-triazole is substituted for 3,5-diethoxycarbonyl-1H-pyrazole and an equivalent amount of 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 4, 2-(1-H-triazol-1-yl)ethyl chloride is isolated 1,2,4-triazole, Aldrich, 43%, used directly after workup).

Sources & evidence

ORD record
ord-0b8576b7ce6b4aa38797f8280337a918
Source dataset
uspto-grants-1991_10
Patent number
US05053411

Reaction notes

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