HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 4-Hydroxypyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| Reactant | 4-Hydroxypyrimidine | HCID 20695 | — |
| Product | 4-Hydroxypyrimidine | HCID 20695 | — |
| Product | 2-(1,6-Dihydro-6-oxopyrimidin-1-yl)ethyl chloride | HCID 19772555 | — |
Reaction Steps
When an equivalent amount of 4-pyrimidone is substituted for 1-ethoxycarbonyl-2H-indazolin-3-one and 2-bromochloroethane is substituted for 1,2-dibromoethane in the procedure of Example 19, 2-(1,6-dihydro-6-oxopyrimidin-1-yl)ethyl chloride is isolated after column chromatography (4-pyrimidone, Aldrich, 34%, B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05053411 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-51b4306f523143c698d0cc229d69e0d4 |
| Source note | uspto-grants-1991_10 |