Methyl iodide → 1-Methyl-3-(4-methylthiazol-2-yl)-pyridinium iodide

HRID 344689Notes

Reaction equation

HRID 344689 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)[S:5][CH:6]=1.[I:13][CH3:14]>C(O)C>[I-:13].[CH3:14][N+:9]1[CH:10]=[CH:11][CH:12]=[C:7]([C:4]2[S:5][CH:6]=[C:2]([CH3:1])[N:3]=2)[CH:8]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 12015543-(4-Methyl-1,3-thiazol-2-yl)pyridine

Product 1

HCID 679250691-Methyl-3-(4-methylthiazol-2-yl)-pyridinium iodide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

8.3 g of [3-(4-methylthiazol-2-yl)-pyridine] and 4.5 cm3 of iodomethane in 30 cm3 of ethanol are left in darkness for 10 days. After filtering, 14.6 g of product is obtained which is recrystallized from ethanol. M.p.=184°-186° C.

Workup

  1. filtrationAfter filtering

Sources & evidence

ORD record
ord-528c6a2a30cd47ec9a73544047d47e18
Source dataset
uspto-grants-1991_10
Patent number
US05053416

Reaction notes

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