Sodium Hydroxide → HCID 19804850, compound

Participants

Reaction Steps

The ethyl 4-t-butoxycyclohexane-1-carboxylate (1 g), thus obtained, was heated on a steam bath with 2M sodium hydroxide solution (10 ml) to which had been added ethanol (2 ml). After about 4 hours a homogenous solution had formed. The reaction mixture was washed with petroleum ether (60-80) and the aqueous phase acidified with concentrated hydrochloric acid. An oil separated which crystallised on cooling and scratching. The solid was collected and recrystallised from petroleum ether (60-80) to yield 4-t-butoxycyclohexane-1-carboxylic acid, m.pt. 100°-105° C.

Provenance & Evidence