1-(4-(1-Ethoxyethoxy)phenyl)ethanol → Benzenemethanol, 4-hydroxy-alpha-methyl-

HRID 344793Notes

Reaction equation

HRID 344793 reaction equation
C(OC([O:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]([OH:15])[CH3:14])=[CH:9][CH:8]=1)C)C>C(O)(=O)C.O1CCOCC1.O>[OH:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]([OH:15])[CH3:14])=[CH:9][CH:8]=1

Participants

3

Reactant 1

HCID 544184991-(4-(1-Ethoxyethoxy)phenyl)ethanol

Product 1

HCID 102803Benzenemethanol, 4-hydroxy-alpha-methyl-

Reagents, catalysts & solvents 1

HCID 70275222Acetic acid dioxane waterSolvent

Procedure

In 700 ml of a mixed solvent of acetic acid/dioxane/water (10/5/5) was dissolved 0.35 mole of a each R-form of fatty acid ester of 1-(4-(1-ethoxyethoxy)phenyl)ethanol, and the mixture was stirred at room temperature for 2 hours. The solvent was distilled under reduced pressure to give an R-form of fatty acid ester of 1-(4-hydroxyphenyl)ethanol.

Workup

  1. distillationThe solvent was distilled under reduced pressure

Sources & evidence

ORD record
ord-bbe37da61439487d9b6cdf49298410b6
Source dataset
uspto-grants-1991_10
Patent number
US05053507

Reaction notes

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