2-Fluoroaniline → 4-bromo-2-fluoroaniline hydrobromide

HRID 344832Notes

Reaction equation

[F:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[Br:9]Br>>[BrH:9].[Br:9][C:7]1[CH:6]=[CH:5][C:3]([NH2:4])=[C:2]([F:1])[CH:8]=1

Participants

Reactant 2

HCID 95842-Fluoroaniline

HCID 24408Bromine

Product 1

HCID 27569714-bromo-2-fluoroaniline hydrobromide

Procedure

adding 2-fluoroaniline to a mixture of bromine and quaternary ammonium bromide in an inert solvent to produce 4-bromo-2-fluoroaniline hydrobromide salt as a precipitate in a mother liquor;

Sources & evidence

ORD record: ord-c618b8807cc240afa9ed8ddc50c57624
Source dataset: uspto-grants-1991_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05053542

Reaction notes

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