HCID 54462223, compound → HCID 9948069, compound

Participants

Reaction Conditions

Reaction Steps

A solution was prepared by dissolving 58.4 g of 2,4'-diallyloxy-5-ethylbiphenyl into 200 ml of tetrahydronaphthalene. The solution was heated at 200° C. with nitrogen gas blowing for 8 hours with stirring, cooled, extracted with 10% sodium hydroxide and washed with n-hexane. The extract, which was acidified with hydrochloric acid, was extracted with diethylether. The extract was washed with an aqueous solution saturated with NaCl, and 10% water solution of sodium hydrogencarbonate, dried with sodium sulfate and concentrated. The concentrate was purified by a silica gel column-chromatography (n-hexane:ethylacetate=15:1) and recrystallized from n-hexane to yield white powder 40 g of 3,3'-diallyl-5-ethyl-2,4'-biphenyldiol having a m.p. of 47°-48° C.

Provenance & Evidence