HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 19894997, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 2-(2-Amino-5-nitrophenoxy)ethan-1-ol | HCID 12537916 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19894997 | HCID 19894997 | 58% |
Reaction Steps
To a stirred suspension of 2 (42 g) and triethylamine (30.4 g) in dichloromethan (400 ml) in an ice bath was added dropwise a solution of methanesulfonyl chloride (25.2 g) in dichloromethane (100 ml). The mixture was stirred for 30 min. and the precipitate was collected by filtration and recrystallized from ethyl acetate to give 33.77 g (58%) of 3: mp 132°-135° C.; MS m/e 276 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05055110 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-4bb92f4496eb435b94eb60c6e31907b8 |
| Source note | uspto-grants-1991_10 |