Methanesulfonyl chloride → HCID 53707178, compound

HRID 345025Notes

Reaction equation

HRID 345025 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[CH3:6][N:7]([CH2:19][CH2:20][C:21]1[CH:26]=[CH:25][C:24]([NH2:27])=[CH:23][CH:22]=1)[CH2:8][C:9]1[O:10][C:11]2[CH:17]=[C:16]([NH2:18])[CH:15]=[CH:14][C:12]=2[CH:13]=1>N1C=CC=CC=1>[CH3:6][N:7]([CH2:19][CH2:20][C:21]1[CH:22]=[CH:23][C:24]([NH:27][S:2]([CH3:1])(=[O:4])=[O:3])=[CH:25][CH:26]=1)[CH2:8][C:9]1[O:10][C:11]2[CH:17]=[C:16]([NH:18][S:2]([CH3:1])(=[O:4])=[O:3])[CH:15]=[CH:14][C:12]=2[CH:13]=1

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 19813445HCID 19813445, compound

Product 1

HCID 53707178HCID 53707178, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Methanesulphonyl chloride (0.21 g, 1.8 mmole) and N-methyl-N-(6-aminobenzofur-2-ylmethyl)-4-aminophenethylamine (see Preparation 2 - 0.24 g, 0.82 mmole) in pyridine (3 ml) when reacted together under conditions similar to those of Example 2, gave the title compound as an oil, yield 0.18 g.

Sources & evidence

ORD record
ord-ff1b1c8f85cd4307bcfc53fe2de637a8
Source dataset
uspto-grants-1991_10
Patent number
US05055473

Reaction notes

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