反应详情

2-Methyl-6-nitroquinoline (18.8 g) was stirred under a hydrogen atmosphere at 30 p.s.i. (equivalent to 206. 8 kPa) for 2 hours in ethanol solution containing 5% Pd/C. The catalyst was then removed by filtration, the filtrate evaporated to small volume in vacuo, and the resultant precipitate collected by filtration, washed with ethanol and ether, and dried to give the title compound, yield 13.2 g, m.p. 188°-189°.

1. customThe catalyst was then removed by filtration
2. customthe filtrate evaporated to small volume in vacuo
3. filtrationthe resultant precipitate collected by filtration
4. washwashed with ethanol and ether
5. customdried