反应详情

Ammonia was passed (for 5 min) into a stirred solution of 1-naphthalenesulfonyl chloride (5.0 g, 22 mmol) and anhydrous Et2O (400 ml) at -78°. The resulting mixture was stirred at -78° for 1 hr, allowed to warm to room temperature, and stirred overnight. The Et2O was removed under vacuum to leave a white powder which was washed with water and dried under vacuum to give 3.2 g (70%) of the title compound as a white powder, m.p. 152°-153° C.

1. custom(for 5 min)
2. customat -78°
3. stirringstirred overnight
4. customThe Et2O was removed under vacuum
5. customto leave a white powder which
6. washwas washed with water
7. customdried under vacuum