N-bromobutanimide → HCID 19993705, compound

Participants

Reaction Steps

A mixture of 3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-hydroxypyrazole (1.0g) and N-bromosuccinimide (0.55g) in chloroform (20ml) was stirred at room temperature for 75 minutes, then washed with water (3×20 ml), filtered through phase-separation paper and evaporated. The residue was purified by dry-column chromatography (eluant ether: hexane 1:1 then 3:1) to give 5-bromo-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-hydroxypyrazole as a buff colored solid, m.p. 145°-151° C.

Provenance & Evidence