Bromine → HCID 19993708, compound

Participants

Reaction Conditions

Reaction Steps

A solution of bromine (2.2 ml) in chloroform (20 ml) was added dropwise to a stirred solution of 2-(2,6-dichloro-4-trifluoromethylphenylazo)-3-oxobutanenitrile (13.0g) in chloroform (20 ml) maintained at 50° C. The solution was then refluxed for 20 minutes, cooled, washed with water (4×50 ml), dried over magnesium sulfate, filtered and evaporated to give 4-bromo-2-(2,6-dichloro-4-trifluoromethylphenylazo)-3-oxobutanenitrile (16.0g) as a brown oil.

Provenance & Evidence