HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinimido indolecarboxylate → trans-3-(2-indolecarboxamido)-2-oxo-4-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinimido indolecarboxylate | HCID 19993581 | — |
| Reactant | trans-3-amino-2-oxo-4-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetamide | HCID 67931351 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | trans-3-(2-indolecarboxamido)-2-oxo-4-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetamide | HCID 69609074 | 68.4% |
Reaction Steps
In 5 ml of dimethylformamide are dissolved 0.2 g of trans-3-amino-2-oxo-4-phenyl 2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetamide and 0.18 g of succinimido 2-indolecarboxylate, and the same reaction and treatment as in Example 12 is carried out to give 0.2 g of trans-3-(2-indolecarboxamido)-2-oxo-4-phenyl-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetamide, m.p. 280°-283° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05055464 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-d24610d15cfd4ccc981f6860615add88 |
| Source note | uspto-grants-1991_10 |