HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34519Generated: October 29, 2026
Thionyl Chloride → 2,2-DI(Acetoxymethyl)propionyl chloride
https://huagongshe.com/reaction/34519
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,2-Bis(acetoxymethyl)propionic acid | HCID 22457842 | — |
| Product | 2,2-DI(Acetoxymethyl)propionyl chloride | HCID 19819011 | — |
Reaction Steps
182 ml (2.5 moles) of thionyl chloride are poured over 218 g (1 mole) of 2,2-bis-acetonxymethyl propionic acid (step 1), followed by refluxing for 8 hours at a batch temperature of approximately 100° C. Excess thionyl chloride is distilled off in a water jet vacuum, leaving a pale yellow, oily product. Yield 236 g (100% of the theoretical).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04762777 |
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| Source dataset | uspto-grants-1988_08 |
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| ORD ID | ord-89530f2a18254553b1cad6d2f1223cf2 |
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| Source note | uspto-grants-1988_08 |
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