HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-Pyrrolidino-1-cyclohexene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Pyrrolidino-1-cyclohexene | HCID 70768 | 95.9% |
Reaction Steps
Cyclohexanone (196.3 g) and pyrrolidine (214 g) in benzene (500 ml) were refluxed under nitrogen with a Dean-Stark apparatus, until no more water separated out. The solvents were then evaporated off under nitrogen, and the residual oil was distilled to give 1-(1-pyrrolidinyl)cyclohexene (290 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05057513 |
| Source dataset | uspto-grants-1991_10 |
| ORD ID | ord-cf667839892a418383ce21ec62dc57f8 |
| Source note | uspto-grants-1991_10 |